一、中心簡介
首都醫(yī)學(xué)科學(xué)創(chuàng)新中心（簡稱創(chuàng)新中心）是北京市新成立的具有獨立法人資格的新型研發(fā)機(jī)構(gòu)。創(chuàng)新中心以推動醫(yī)學(xué)科學(xué)發(fā)展、改善人類健康為目標(biāo)，開展生物醫(yī)學(xué)研究，致力于提升醫(yī)學(xué)科學(xué)創(chuàng)新與成果轉(zhuǎn)化能力，提高疾病診斷和治療水平。我們將匯聚世界高水平科學(xué)家，與首都醫(yī)學(xué)教育和科學(xué)研究優(yōu)質(zhì)資源緊密合作，打造多學(xué)科交叉融合的科研平臺，綜合自由探索、醫(yī)學(xué)目標(biāo)導(dǎo)向、有組織科研等途徑，實踐新型科研模式和體制機(jī)制，逐步推進(jìn)醫(yī)教研產(chǎn)的深度融合，培養(yǎng)適應(yīng)醫(yī)學(xué)科學(xué)創(chuàng)新發(fā)展的優(yōu)秀人才。
二、實驗室介紹
王立銘，首都醫(yī)學(xué)科學(xué)創(chuàng)新中心資深研究員，遺傳與分子醫(yī)學(xué)研究所所長，博士生導(dǎo)師。
實驗室長期關(guān)注機(jī)體代謝的神經(jīng)生物學(xué)調(diào)控機(jī)理研究。在Nature、Nature Neuroscience、PNAS、e Life、Cell Research等知名期刊發(fā)表多篇研究論文。同時致力于大眾科學(xué)傳播和教育，出版專著《吃貨的生物學(xué)修養(yǎng)》《上帝的手術(shù)刀》《生命是什么》《笑到最后》《給忙碌者的病毒科學(xué)》等科普書籍，發(fā)行量超30萬冊，先后獲得國家圖書館“文津圖書獎”、科技部全國優(yōu)秀科普作品、“吳大猷科普著作獎”等獎勵。
掃碼了解更多_二維碼（請點擊鏈接查看詳情）
三、實驗室研究方向
包括人類在內(nèi)，動物的生存和健康很大程度上依賴于對機(jī)體能量和必需營養(yǎng)物質(zhì)水平的精確調(diào)節(jié)和維持，而中樞神經(jīng)系統(tǒng)在這方面發(fā)揮了不可或缺的重要功能。通過實時的感知機(jī)體內(nèi)部的能量和營養(yǎng)物質(zhì)儲備，以及環(huán)境中食物的分布，中樞神經(jīng)系統(tǒng)可以通過精密的行為調(diào)節(jié)，保證動物機(jī)體的代謝平衡。而這一調(diào)控機(jī)制一旦被破壞，將可能引發(fā)包括進(jìn)食障礙、肥胖癥在內(nèi)的一系列神經(jīng)和代謝系統(tǒng)疾病。
實驗室對神經(jīng)系統(tǒng)與代謝系統(tǒng)相關(guān)聯(lián)的生物學(xué)問題有廣泛的興趣。近期的研究工作將主要利用定量行為分析、活體鈣成像、遺傳篩選和分析、單細(xì)胞轉(zhuǎn)錄組和環(huán)路追蹤等技術(shù)，在果蠅和小鼠模型中研究如下兩個相互獨立但互相關(guān)聯(lián)的生物學(xué)問題：
l 神經(jīng)系統(tǒng)如何參與機(jī)體能量和重要營養(yǎng)物質(zhì)代謝的調(diào)控
l 動物各器官如何協(xié)同參與機(jī)體代謝的調(diào)控和代謝病的發(fā)生
四、崗位信息
崗位1：科研助理（若干）
01、崗位職責(zé)
1.協(xié)助團(tuán)隊或獨立開展課題研究；
2.參與實驗室日常管理，提供公共事務(wù)支持。
02、任職要求
1.細(xì)胞生物學(xué)、神經(jīng)生物學(xué)相關(guān)專業(yè)碩士及以上學(xué)歷，有相關(guān)實驗技術(shù)經(jīng)驗者可放寬到本科；
2.抗壓能力強(qiáng)，熱愛科研，有志于繼續(xù)從事科研工作；
3.品行端正，動手能力強(qiáng)，工作認(rèn)真負(fù)責(zé)，具備良好的團(tuán)隊協(xié)作能力；
4.通過CET-6或同等英語水平，或有攻讀研究生計劃者優(yōu)先。
03、研究方向
1.進(jìn)行細(xì)胞方面的相關(guān)科研實驗，日常的細(xì)胞事務(wù)管理、質(zhì)粒的轉(zhuǎn)染、穩(wěn)轉(zhuǎn)細(xì)胞系的構(gòu)建、細(xì)胞染色、成像、KO文庫和代謝物篩選等；
2.進(jìn)行神經(jīng)環(huán)路方面相關(guān)科研實驗，腦立體定位注射、光纖記錄、光/化學(xué)遺傳學(xué)、雙光子活體成像、組織透明化成像等；
3.進(jìn)行果蠅神經(jīng)環(huán)路方面相關(guān)科研實驗，包括行為學(xué)檢測、在體及離體鈣成像、熒光腦片拍攝、光遺傳學(xué)、果蠅庫管理等。
崗位2：博士后（2名）
01、崗位職責(zé)
1.在導(dǎo)師及合作導(dǎo)師共同指導(dǎo)下參與實驗室的課題研究；
2.協(xié)助處理實驗室公共事務(wù)。
02、任職要求
1.獲得或即將獲得生物學(xué)/基礎(chǔ)醫(yī)學(xué)相關(guān)領(lǐng)域博士學(xué)位，畢業(yè)時間一般不超過三年；
2.以第一作者身份在領(lǐng)域內(nèi)主流期刊發(fā)表過或即將發(fā)表研究論文；
3.具備獨立開展科研工作能力，對科研有熱情和嚴(yán)謹(jǐn)認(rèn)真的態(tài)度，有團(tuán)隊合作精神；
4.對代謝和代謝相關(guān)疾病有強(qiáng)烈興趣、有細(xì)胞生物學(xué)或神經(jīng)生物學(xué)研究背景者同等條件下優(yōu)先考慮。
五、福利待遇
1.根據(jù)應(yīng)聘者的工作經(jīng)驗和能力，提供具有市場競爭力的薪酬（詳情面談）；
2.享受五險一金、帶薪年假、體檢和補充醫(yī)療保險等；
3.支持個人發(fā)展，提供必要的工作相關(guān)專業(yè)培訓(xùn)；
4.為有科研熱情且有一定科研能力的應(yīng)聘者提供充足的深造機(jī)會。
六、申請方法
應(yīng)聘者請將以下材料按照如下順序打包發(fā)送至igm@cimrbj.ac.cn，請【點擊下方“立即投遞/投遞簡歷”，即刻進(jìn)行職位報名】，各項材料以“姓名+資料名稱”命名，郵件主題請注明“應(yīng)聘者名字+具體應(yīng)聘職位”。
1.個人簡歷、研究興趣或計劃；
2.學(xué)術(shù)成果或獎勵清單（如有）；
3.2名推薦人的姓名及聯(lián)系方式（僅限博士后應(yīng)聘）；
4.其他能證明科研能力的相關(guān)電子文件。
聯(lián)系人：
聯(lián)系地址：北京市豐臺區(qū)右安門外西頭條10號-首都醫(yī)學(xué)科學(xué)創(chuàng)新中心
本招聘長期有效，至招聘到合適人選為止。
ABOUT CIMR
Chinese Institutes for
Medical Research (CIMR) is a newly founded institution dedicated to fundamental
and translational medical research. The CIMR is located at the main campus of
the
ABOUT IGM
The Institute for
Genetics and Molecular Medicine (IGM) is dedicated to advancing research on
congenital genetic diseases, cancer, metabolic disorders, and immune-related
diseases. We focus on integrating genetic research with the development of
diagnostic and therapeutic technologies, aiming to translate disease research
into clinical applications. Leveraging the abundant clinical resources of
affiliated hospitals of
Laboratory Introduction
Liming Wang is
Investigator and Director of Institute for Genetics and Molecular Medicine,
Chinese Institutes for Medical Research,
The laboratory has long focused on researching the neurobiological regulatory mechanisms of body metabolism. It has published numerous research papers in renowned journals such as Nature, Nature Neuroscience, PNAS, eLife, and Cell Research. Meanwhile, it is committed to public science communication and education, publishing popular science books including The Biology Cultivation of Foodies, God's Scalpel, What Is Life, Laughing to the End, and Virus Science for the Busy, with a circulation of over 300,000 copies. The laboratory has successively won awards such as the "Wenjin Book Award" from the National Library of China, the National Excellent Popular Science Works Award from the Ministry of Science and Technology, and the "Wu Dayou Popular Science Writing Award".
Lab website:QR→（請點擊鏈接查看詳情）
Laboratory Research Directions
The survival and health of animals, including humans, largely depend on the precise regulation and maintenance of energy and essential nutrient levels in the body, and the central nervous system (CNS) plays an indispensable role in this regard. By real-time sensing of energy and nutrient reserves within the body, as well as the distribution of food in the environment, the CNS ensures metabolic balance in animals through sophisticated behavioral regulation. Once this regulatory mechanism is disrupted, it may trigger a series of neural and metabolic diseases, including eating disorders and obesity.
Our laboratory has broad interests in biological questions related to the interaction between the nervous system and metabolic system. Our recent research will primarily use techniques such as quantitative behavioral analysis, in vivo calcium imaging, genetic screening and analysis, single-cell transcriptomics, and circuit tracing in Drosophila and mouse models to investigate the following two independent but interrelated biological questions:
How does the nervous system participate in the regulation of energy and essential nutrient metabolism in the body?
How do various organs in animals collaborate in the regulation of body metabolism and the occurrence of metabolic diseases?
Open Positions
Research Assistant
Main Responsibilities
a. Assist in or independently conduct research projects.
b. Participate in laboratory management and provide administrative support.
Qualifications
a. Master’s degree or higher in cell biology, neurobiology, or related fields; bachelor’s degree holders with relevant experimental experience will also be considered on a priority basis.
b. Strong resilience, passion for research, and commitment to a scientific career.
c. High ethical standards, excellent hands-on skills, diligence, and teamwork abilities.
d. Priority given to candidates with CET-6 certificate or equivalent proof of English proficiency, or those planning to pursue graduate studies.
Research Directions
a. Engage in cell-related experiments, including cell culture management, plasmid transfection, stable cell line construction, cell staining, imaging, KO library screening, and metabolite screening.
b. Perform neurocircuitry-related experiments, such as stereotaxic brain injections, fiber photometry, optogenetics/chemogenetics, two-photon in vivo imaging, and tissue clearing imaging.
c. Engage in Drosophila neurocircuitry research, including behavioral assays, in vivo/ex vivo calcium imaging, fluorescent brain slice imaging, optogenetics, and fly stock management.
Postdoctoral Researcher
Main Responsibilities
a. Conduct independent research under the guidance of the principal investigator (PI) and co-mentors, while collaborating with team members.
b. Assist in laboratory management and public affairs.
Qualifications
a. Ph.D. degree (or expected to graduate within 6 months), generally within three years of graduation, in biology, basic medicine, or related fields.
b. First-author publication in a peer-reviewed journal (or accepted for publication).
c. Ability to conduct independent research, strong passion for science, rigorous attitude, and teamwork spirit.
d. Priority given to candidates with a strong interest in metabolism/metabolic diseases (e.g., neuro-metabolism or metabolic disorders in cancer) or backgrounds in cell biology/neurobiology.
Welfare Treatment
a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).
b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c. Opportunities for career development and available professional guidance.
d. Ample opportunities for further academic promotion for outstanding candidates.
How to apply
Interested applicants should compile the following materials in order and send them to igm@cimrbj.ac.cn, naming each file as "Name + Document Title" and using the email subject line "Applicant Name + Position Applied For":
a. CV and a detailed statement of research interests and future plans.
b. List of academic achievements/awards .
c. Names and contact details of two referees (for postdoctoral applicants only).
d. Additional supporting materials (e.g., representative research papers, project reports) to demonstrate research capabilities.
Contact Person: Ms. Ren
Email: igm@cimrbj.ac.cn
Address: No.10
Xitoutiao, Youanmenwai, Fengtai District,
This recruitment will remain open until suitable candidates are selected.
Candidates are encouraged to apply as early as possible.
信息來源于網(wǎng)絡(luò)，如有變更請以原發(fā)布者為準(zhǔn)。
來源鏈接：
https://mp.weixin.qq.com/s/MoFcavr9RCZ-kg7fzqxDbw
更多最新博士后招收資訊請關(guān)注：
【
【
